There are now 13 novels and a bunch of short stories in this series which I flippantly described to my son as "He's a werewolf and she's an FBI agent: they fight supernatural crime". The covers feature a dark haired woman wearing a black sleeveless vest and tight pants; she might, perhaps, have some Asian ancestry. The books feature Lily Yu, a short Chinese-American woman who was born and raised in San Diego and tends to wear the sort of jacket and pants combination that countless police detectives have made a virtual uniform on television. Her Grandmother becomes a major plot elephant.
Worst aspect of this series: werewolves are all polyamorous males with low fertility and major fears of commitment; but, they know as soon as they have impregnated a female human, at which point they start making plans to care for the baby and adopt it if it's male. (There appear to be no gay or bi werewolves, although there is a fair amount of representation of LGBTQ people otherwise, some of whom are major characters.)
Second worst aspect of this series: once in a while a werewolf is granted A Mate by their Goddess-whom-they-don't-worship, in which case it is Bonding At First Sight for both the werewolf and the woman. That's not the same as love, mind you. The Goddess enforces the bond by inflicting pain on both parties when they get too far away from each other; the precise distance varies a lot over time. This happens at least twice in the series.
Best aspect of this series: the world-changing events actually change the world, repeatedly and with well-thought-out consequences.
Contains multiple universes, horrors from before the beginning of time, species constructed to the specification of gods, limitations on deific powers, demons that don't really make sense, and the persistent feeling that somebody knows what's going on but won't tell you For Reasons.