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Folic acid has been shown to help prevent birth defects, such as spina bifida. A systematic review of four trials involving 6425 women found that the chance of having a baby with a neural tube defect is reduced by about 75% if women take the supplements prior to conception and for the first two months of pregnancy (relative risk 0.28, 95% confidence interval 0.13 to 0.58).

from http://www.nhs.uk/news/2009/09September/Pages/SpinaBifidaFolicAcidCall.aspx

Remember, science is repeatable, reliable, and analyzable. If it doesn't meet all three of those criteria, it's not science.
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